Tarka® Trandolapril/Verapamil HCI
Tarka Trandolapril/Verapamil HCI this Brand Name product is manufactured by Abbott. Tarka contains the combination of trandolapril and verapamil is used to treat high blood pressure.
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What is TarkaTrandolapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Verapamil is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. The combination of trandolapril and verapamil is used to treat high blood pressure . Trandolapril and verapamil may also be used for other medical purposes, to be used as recommended by your doctor.
Additional Info on TarkaTarka capsules contain two active ingredients, trandolapril and verapamil. Trandolapril is a type of medicine called an ACE inhibitor and verapamil is a type of medicine called a calcium channel blocker. These are both medicines used to lower high blood pressure. They work in different ways to lower high blood pressure. Verapamil works by slowing down the movement of calcium through muscle cells that are found in the heart and the walls of blood vessels. It does this by blocking 'calcium channels' on these muscle cells. Calcium is needed by the muscle cells in order for them to contract. By depriving them of calcium, verapamil causes the muscle cells to relax. This action of verapamil has two main effects; it slows down the rate at which the heart beats and it allows the blood vessels in the body to widen. When the heart beats more slowly, the pressure at which the blood is pumped out of the heart is reduced. When the blood vessels in the body relax and widen, this decreases the resistance that the heart has to push against in order to pump the blood around the body. Both these actions reduce the pressure within the blood vessels. This means verapamil can be used to lower high blood pressure. ACE inhibitors such as trandolapril work by blocking the action of a compound in the body called angiotensin converting enzyme (ACE). Normally ACE produces another compound called angiotensin II, as part of the body's natural control of blood pressure. Angiotensin II causes blood vessels to constrict and narrow, which increases the pressure within the blood vessels. As trandolapril blocks the action of ACE, it reduces the production of angiotensin II. This means that the blood vessels are allowed to relax and widen and the pressure within them therefore falls. The overall effect of both these medicines is a drop in blood pressure. As they work in different ways they have an additive effect on high blood pressure. The combination is used when high blood pressure has not been lowered sufficiently by taking trandolapril or verapamil alone.
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