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Comfortis® for Dogs and Cats

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Brand Name Products Price Add to Cart
COMFORTIS Chewable PINK 5 to 10 lbs 140mg 6 Tablets
COMFORTIS Chewable ORANGE 10 to 20 lbs 270mg 6 Tablets
COMFORTIS Chewable GREEN 20 to 40 lbs 560mg 6 Tablets
COMFORTIS Chewable BLUE 40 to 60 lbs 810mg 6 Tablets
COMFORTIS Chewable BROWN 60 to 120 lbs 1620mg 6 Tablets

Product Details for Comfortis® for Dogs and Cats

Buy Comfortis for Dogs and Cats at Global Pharmacy Plus with confidence knowing that your are buying brand name Comfortis manufactured by Elanco Animal Health that has been sourced in Europe. The cost of Comfortis is less expensive in Europe and we are passing on the savings to you.

Comfortis for Dogs / Puppies:

Pink Box (2.3 to 4.5kg) = 5-10 lbs (Pink Box)
Orange Box (4.6 to 9kg) = 10.1-20 lbs (Orange Box)
Green Box (9.1 to 18kg) = 20.1-40 lbs (Green Box)
Blue Box (18.1 to 27kg) = 40.1-60 lbs (Blue Box)
Brown Box (27.1 to 54kg) = 60.1-120 lbs (Brown Box)

Comfortis for Cats / Kittens:

Pink Box 2.3 to 4.5kg) = 4-6 lbs (Pink Box)
Orange Box (4.6 to 9kg) = 6.1-12 lbs (Orange Box)
Green Box (9.1 to 18kg) = 12.1-24* lbs (Green Box)
*Cats over 24 lbs should be administered the appropriate combination of tablets.

Comfortis chewable tablets are indicated for the treatment and prevention of flea infestation with Ctenocephalides felis in dogs and cats and as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD). Comfortis chewable tablets are unscored tan to brown, or speckled, round, flat, bevelled-edge tablets, plain on one side and embossed with a number on the other side. These tablets are available in 3.9-6.5Kg - 270mg. 6.1-9.4Kg - 425mg. 9.5-14.7Kg - 665mg. 14.8-23.1Kg - 1040mg. 23.2-36.0Kg - 1620mg.

Comfortis chewable tablets can be administered at the recommended dose with the following advice:

Comfortis tablets can be administered by the oral route with or without food. If given without food, administration should immediately follow feeding. Dosing on an empty stomach may reduce the residual efficacy of Comfortis tablets.

The tablets should be administered at monthly intervals.

If vomiting occurs within an hour of administration and the tablet is visible, re-dose with another full dose.

If a dose is missed, administer the veterinary medicinal product with the next offering of food and resume a monthly dosing schedule.

In the case of heavy flea infestations, fleas may persist for a period of time after administration of the product due to the emergence of adult fleas from pupae already in the environment. Regular monthly treatment with Comfortis breaks the fleas' life cycle. This is achieved by the capability of spinosad to rapidly kill adult fleas and therefore greatly reduce egg production.

Do not use in dogs under 14 weeks of age.

Do not use in case of known hypersensitivity to the active substance or to any of the excipients.

Special precautions for use in animals

Use with caution in dogs with pre-existing epilepsy.

Accurate dosing is not possible in dogs weighing less than 3.9kg and therefore the use of Comfortis tablets is not recommended in these patients.

Special precautions to be taken by the person administering Comfortis tablets to animals

Accidental ingestion may cause adverse reactions.

In case of accidental ingestion, seek medical advise immediately and show package leaflet or label to the physician.

Wash hands after administering product.

For animal treatment only.

Spinosad has been shown to be a substrate for P-glycoprotein (PgP). Spinosad could therefore interact with other PgP-substrates (for example, digoxin and doxorubicin) and possibly enhance adverse reactions from such molecules or compromise efficacy.

Post marketing reports following the concomitant use of Comfortis with 'off label' high doses of ivermectin indicate that dogs have experienced trembling/twitching, salivation/drooling, seizures, ataxia, mydriasis, blindness and disorientation.

Clear PTCFE/PE/PVC blister pack sealed with aluminum foil containing six chewable tablets.

Carton packages containing one or six blister packs.

The most frequently observed adverse event is vomiting, which most commonly occurs in the first 48 hours after dosing. In the majority of cases, vomiting is transient, mild and does not require symptomatic treatment.

Other adverse reactions were uncommon or rare, and included lethargy, anorexia, diarrhea, ataxia and seizures.

At doses up to 100mg/kg bodyweight per day for 10 days, the only clinical symptom of overdose was vomiting. Mild elevations of ALT (alanine aminotransferase) occurred in all dogs treated with Comfortis, although values returned to their baseline by day 24. Phospholipidosis (vacuolation of lymphoid tissues) also occurred; although this was not related to clinical signs in dogs treated up to 6 months.

In laboratory species (rats and rabbits) spinosad has neither produced any evidence of teratogenic, foetotoxic or maternotoxic effects, nor shown any effect on the reproductive capacity in males and females.

In pregnant bitches and during lactation, the safety of spinosad has not been sufficiently established.

The safety of the product in male dogs used for breeding has not been determined.

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